How to convert a pdf file to a scorm package in a few clicks. Adding thalidomide t and lenalidomide r to the melphalan and prednisone mp. Lets follow the same steps here, but this time we wont check the display as icon option. How to convert a powerpoint presentation to a scorm package. Thalidomide thalomid side effects, dosage, interactions. Thalidomide can increase this chance for birth defects. The drug, then designated as k17, was thought to have sedative effects superior to those of comparator drugs and was thought to be virtually nontoxic. The trouble i have is that my title page is defined by the top section of yaml.
This leaflet has been written to help you understand more about thalidomide. Thalidomide is the generic form of the brandname drug thalomid, prescribed along with a corticosteroid dexamethasone to treat multiple myeloma a malignancy in plasma cells when a person is. If lenalidomide is used during pregnancy, it may cause birth defects or embryofetal death. In this article, we will tell you exactly how to insert an object as an icon you select. Excel provides a plethora of features for organizing, manipulating, and handling your data. Ppt thalidomide powerpoint presentation free to download. Select this option if you dont want such images hyperlinked. Thalomid tm thalidomide capsules 15 july 1998 revised package insert 2 23 prescribers 24 thalomid tm thalidomide may be prescribed only by licensed prescribers who are 25 registered in the s. The thalidomide tragedy, as many call it, galvanized congress into passing the 1962 kefauverharris amendments to the 1938 food, drug, and cosmetic act, hereafter called the 1962 amendments. Rearrange individual pages or entire files in the desired order. In this case, you dont have to insert the pdf as an object or attach it as an action. United states prescribing thalidomide on july 16, 1998, the fda approved the use of thalidomide for the treatment of lesions associated with erythema nodosum leprosum enl. Thalidomide proves useful for skin lesions and multiple myeloma in the mid1960s, scientists determined that thalidomide was an effective treatment for erythema nodosum leprosum.
You insert an object or a file into a document, presentation, spreadsheet, or other microsoft office 2003 or microsoft office xp file. Prescription drug labeling from discovery to approval distancecourse in regulatory affairs lehigh university john j spaltro, ph. Thalomid uses generic names in all descriptions of drugs. Thalomid tm thalidomide capsules 15 july 1998 revised package insert 6 144 under the curve auc is proportional to dose in healthy subjects, the observed peak 145 concentration c max increased in a less than proportional manner see table 1 below. Click the image and it will be inserted into the slide. Manipulation of microsoft word and powerpoint documents. Creating powerpoint presentations with python practical. To do this, open the pdf file and go to the page whose contents you want inserted into the powerpoint presentation. Ways to convert powerpoint into an interactive elearning module. In the excel file, head over to the insert tab and then click the object button. Now we are going to embed that information into a new powerpoint file based on a given powerpoint template file.
Thalidomide thalomid was introduced in the 1950s as a sedative prescribed for nausea and insomnia in pregnant women. Here are the steps to inserting a pdf file into a word document. Multiple drug combinations of bortezomib, lenalidomide, and. In females of reproductive potential, obtain 2 negative pregnancy. How to convert powerpoint into an interactive elearning. Inserting a pdf as an image is a quick way to present flat data in a noninteractive fashion. By connor th, mackenzie ba, debord dg, trout db, ocallaghan jp. Go to insert tab object double click package in the list of options then the create package dialog will appear where it will guide you through the attachment process. The icon is blank when you insert an object or a file into. Interactive learning, teaching and evaluation resources created with geogebra can be shared and used by everyone at the geogebra app for powerpoint lets you insert interactive geogebra materials into your presentation.
Initially marketed as contergan, thalidomide was prescribed as a nonbarbiturate hypnotic sedative able to produce deep sleep without hangover or risk of dependency. Exemestane is distributed extensively into tissues. You must follow the contraception advice given to you by your doctor. That means everyone in your organization can transact business and collaborate faster in their favorite office apps. This will insert the pdf first page only as objects cannot span pages just as in earlier versions, without converting the pdf. If you just want to add word content to powerpoint, dont check the display as icon option. Apr, 2010 united states prescribing thalidomide on july 16, 1998, the fda approved the use of thalidomide for the treatment of lesions associated with erythema nodosum leprosum enl.
The pdf file should be the first option within the insert dialog window. And editing the graphic in powerpoint, for me anyway, would be faster than editing the graphic in illustratorespecially considering the file is going to end up in powerpoint eventually anyway. The antiangiogenic byproduct inhibits angiogenesis from existing vessels and also prevents formation of new vessels in tissues and organs. You can insert them wherever needed using \againframe with the label you chose in filea. Niosh list of antineoplastic and other hazardous drugs in healthcare settings, 2016. May not introduce drug into interstate commerce if in. The last thing i would like to be able to do is to add an image to the title page of my pdf document. If your pdf is in a presentation format, the conversion should be no problem. In some cases, health care professionals may use the trade name thalomid when referring to the generic drug name thalidomide. Embryo fetal toxicity if thalomid is taken during pregnancy, it can cause severe birth defects or embryofetal death. So you have a big presentation coming up and you want your powerpoint slides to look great. This emedtv page takes a look at the specific warnings and precautions with thalidomide that are designed to help ensure the safety of using this drug. Because of thalidomide s potential for causing birth defects, the distribution of the drug was permitted only under tightly controlled conditions.
Thalomid tm thalidomide capsules 15 july 1998 revised. The reasons a drug has not been awarded ma by a country are because the company. Thalidomide is a known human teratogen that causes severe lifethreatening human birth defects. Knowledge and time are the 2 most valuable resources in the world that we currently live in and, now, we have many opportunities to benefit from learning quickly and easily with the help of elearning technologies. Save your presentation powerpoint or keynote as a pdf without the video open the deck in acrobat x. Department of health and human services, centers for disease control and prevention, national institute for occupa. You can spruce up your powerpoint presentation by including videos. Do not automatically hyperlink screenshot powerpoint 20 and newer versions when you use insert screenshot and capture an image from the internet explorer web browser, powerpoint can make the image a hyperlink that points to the web page that you take the screenshot of. How to include existing pdf slides into my beamer presentation.
To insert a pdf file as an object into a powerpoint presentation, you make it available to those youre sharing the presentation with. It is administered by a healthcare professional as an injection into your vein intravenously, or iv or under your skin subcutaneously, or sc. Sep 01, 2019 it is not known if thalomid passes into your breast milk and can harm your baby. How fda approves drugs and regulates their safety and effectiveness congressional research service summary the food and drug administration fda, a regulatory agency within the department of health and human services, regulates the safety and effectiveness of drugs sold in the united states. But how to make sure that your employees really open the files and carefully study them. May cause eye, skin, or respiratory system irritation.
However the drug was also found to cure morning sickness in pregnant. Word provides the ability to insert objects into word documents. How to put video inside pdf powerpoint templates and. Thalomid thalidomide capsules, for oral use initial u. Thalidomide was developed by the swiss pharmaceutical company ciba in 1953 and then was introduced by the german pharmaceutical company chemi grunenthal in 1956 rajkumar, 2004. Kyprolis carfilzomib for relapsed or refractory multiple. Kyprolis carfilzomib is indicated in combination with dexamethasone or with lenalidomide plus dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy. If you have a video file on your computer, you can embed it into your presentation. This post is part of a series called how to use powerpoint in 60 seconds quick video tutorials. Insert pdf file content into a powerpoint presentation powerpoint. To show content from a pdf on a slide take a picture of the part of a pdf that you want, and paste it on your slide. For example, the drug was known as distaval in the uk and australia, but was called. Niosh list of antineoplastic and other hazardous drugs in.
Nov 08, 2019 pomalyst is a thalidomide analogue indicated, in combination with dexamethasone, for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy 1. Velcade must not be administered into your spinal fluid intrathecally. Mar 11, 2012 a powerpoint presentation on the effects of thalidomide and how it changed the process of drug trialling. Now, adobe document cloud esigning and pdf tools are built right into microsoft office 365. How to insert word documents into powerpoint in 60 seconds. Convert an illustrator vector graphic to a powerpoint. Thalidomide in combination with chemotherapy in treating elderly.
Added to a thalidomide analogue and dexamethasone 5. Cannot insert object error when inserting pdf files. Thalomid thalidomide dose, indications, adverse effects. Learn how to insert objects in microsoft powerpoint at get the complete tutorial free. Pomalyst is a thalidomide analogue indicated, in combination with dexamethasone, for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy. Nphthalimido glutarimide, is an immunomodulatory agent. How to link or embed an excel worksheet in microsoft powerpoint. Finially i figured out a way to solve this pdf attachment problem on excel. Thalomid fda prescribing information, side effects and uses. The new food and drug administration drug package insert.
Sep 12, 20 these resources will help your pupils understand the thalidomide tragedy, how it affected its victims, and what could have been done to prevent it. Because of thalidomides potential for causing birth defects, the distribution of the drug was permitted only under tightly controlled conditions. The good news is that its quick and easy to add custom themes to powerpoint for a unique look. Insert pdf file content into a powerpoint presentation. Insert a pdf file as an object into a powerpoint presentation. Currently, the treatment decisions in elderly patients with.
Velcade is prescribed by a doctor experienced in the use of medications to treat cancer. More and more of my presentations start to use video, and my preferred format for emailingdropboxing decks is pdf, so how do you insert a video in pdf. I use the knit pdf button in rstudio to turn it into a pdf. Thalidomide, a drug prescribed to expectant mothers in the late 1950s, baffles scientists to this day. Annotated collection of english and german web resources providing information on the drugs physicochemical properties, effects, side effects, the german contergan disaster in the early 1960s, and the current use of thalidomide.
Us regulatory response to thalidomide 19502000 the. Create and update powerpoint reports using r displayr. Thalomid and other medicines may affect each other, causing serious side effects. Furthermore, when you insert an object, you can also choose to. How to select custom icon for the object inserted into. It even allows you to rename the file name of the attachment. Start by opening both the excel worksheet and the powerpoint presentation you want to edit at the same time. Learn more about ispring suite authoring tool and get a free trial at this tutorial shows how to convert a powerpoint presentation to a scorm package. Risk management in the united states jamie wilkins parker, pharm. To keep a pdf file as a support document for your presentation insert the entire pdf into the presentation as an object that you can open and view during your presentation. However the drug was also found to cure morning sickness in pregnant women was available as otc drug. Change embedded file name in word, excel and office. The empirical formula for thalidomide is ch10n2o4 and the gram molecular weight is 258. Male patients must use barrier contraception latex condom during sexual intercourse with a woman of reproductive potential while on therapy, during interruptions, and for 4 weeks after discontinuing therapy, even if he has undergone a successful vasectomy.
Graham mayor microsoft word mvp 20022019 for more word tips and downloads visit my web site. Nearly 60 years ago thalidomide was prescribed to treat morning sickness in pregnant women. One of these unique features is inserting a pdf directly into excel. Risk management in the united states food and drug. Thalidomide 200 mg once daily combined with dexamethasone 40 mg daily on days 14, 912, and 1720 of a 28day cycle, with cycles repeated at 28day intervals. Women who are pregnant or could become pregnant must follow strict rules when using thalidomide. What are known examples of drugs that racemizestereoconvert. When you embed an object in office documents, the original file name and the default icon will be selected automatically. The underlying assumption is that r is your computational engine and that you are trying to get outputs into powerpoint. How fda approves drugs and regulates their safety and. In the insert object box, select create from file, and then enter the pdf file location. How to convert a pdf to a scorm package in a few seconds.
Sometimes, there is a shape or vector graphic from a popular stock photo site that id like to edit and use in powerpoint. When a woman takes thalidomide early in her pregnancy between the 20 th and 36 th day after conception or the 3450 th after the start of the last period, there is a chance of at least 20% or more to have a baby with birth defects. Difficult for women of childbearing age metabolism of thalidomide is not well understood and drug may be stored in fat in which case it could be in the body for years thalidomide can take people out of wheelchairs but it can put people into wheelchairs, too. Steps to convert ppt into elearning using adobe captivate 2017 syed amjad ali swift is an innovative elearning services company that provides endtoend elearning solutions to corporates, academia and training providers in india and throughout the world. The rise, fall and subsequent triumph of thalidomide. Using icons to represent the object you insert in word is a great choice, as an icon is probably more recognizable by people. The primarily unregulated distribution of thalidomide pressed the fda into soliciting drug applications from several companies that were investigating the drug. Ppt prescription drug labeling powerpoint presentation. Celgene corporation gained approval to formally market the drug. A reversal back to the ketone results in a mix of r and s enantiomers. Powerpoint will automatically paste this into your presentation once youve selected the area. Here is a step by step process, if you are looking for changing the embedded file name in any office documents like word, excel or powerpoint. The distribution of exemestane and its metabolites into blood cells is negligible. Tell your healthcare provider about all the medicines you take, including prescription and overthecounter medicines, vitamins, and herbal supplements.
Although i cant think of any drug examples other than thalidomide, heres information on thalidomides mechanism. Material may be irritating to the mucous membranes and upper respiratory tract. The purpose of the package insert is to provide complete and unbiased prescribing and safety information to health professionals. Steps to convert ppt into elearning using adobe captivate. Thalidomide contergan annotated collection of links. No notable activity was seen with this drug in any of these early trials, and enthusiasm for continuing research of thalidomide as an anticancer agent disappeared.
Embryofetal toxicity and venous thromboembolism see full prescribing information for complete boxed warning. To bring you great quality, smallpdf has partnered with solid documents that offers the best conversion out there. Perhaps no other drug in modern medicine rivals the dramatic. The quality of the pdf file is reduced with this method, but you can open the full pdf file by doubleclicking the image when viewing or editing in normal view. Later, it was found to be the cause of severe birth defects in children whose mothers had taken the drug during the first trimester of pregnancy. The 55 year history of the drug thalidomide is shakespearean in. Place your cursor by clicking on the area where you wish to insert the pdf document. Exemestane is 90% bound to plasma proteins and the fraction bound is independent of the total concentration. Lenalidomide, a thalidomide analogue, caused limb abnormalities in a developmental monkey study. How to link or embed an excel worksheet in a powerpoint. In 1968, a two line warning placed on the isoproterenol inhaler package is. They will learn about the drug development process and the role of animal research within it and consider the ethical implications of science in society.
A free powerpoint ppt presentation displayed as a flash slide show on id. Powerpoint 2016 tutorial inserting objects microsoft. Creating powerpoint presentations with python and pandas. Another way that you can work with a word document is to insert some of the content from inside it into the presentation. I compare and contrast three tools for creating and updating powerpoint reports using r. Now its easier than ever to get esignatures right from the solutions you use every day.
It uses a similar set of steps to inserting as an image, but does something different as a result. Do not take thalidomide if you are pregnant or could become pregnant. It is ideal for presenting data contained within other. Any changes you make to these geogebra materials are saved in your powerpoint file. Pdf instruction manuals, guides, and howto articles are a popular way of transferring knowledge. Thalidomide passes into semen and there is potential for malemediated teratogenicity. In short, one can add images, tables and text into documents from r. Nov 09, 2017 difficult for women of childbearing age metabolism of thalidomide is not well understood and drug may be stored in fat in which case it could be in the body for years thalidomide can take people out of wheelchairs but it can put people into wheelchairs, too.
The chiral carbon of thalidomide can tautomerize in basic conditions into an enol, which is achiral. The good news is it only involves a few simple steps to do it. Under object type, select adobe acrobat document and. Linking or embedding an excel worksheet into a powerpoint presentation is actually pretty straightforward, and the process for doing either is almost identical. How to insert a pdf into powerpoint online tech tips. Learn more about revlimid, a treatment option for multiple myeloma. Information for the patient thalidomide celgene 50 mg hard capsules thalidomide warning thalidomide causes birth defects and foetal death.
Use your mouse to select the area around your partial screenshot. From these events, the public scrutinized the fdas policies and methods for drugs. Thrombocytopenia has been reported with ninlaro with platelet nadirs typically occurring between days 1421 of each 28day cycle and recovery to baseline by the start of the next cycle. Insertembed pdf file in powerpoint 2010 presentation. Ninlaro ixazomib capsules, for oral use hepatotoxicity.633 867 88 3 1326 1205 680 1514 438 1414 1392 1032 604 239 656 1374 1483 1006 1308 564 1374 1056 147 966 866 799 498 710 661 498 145 1654 505 1394 1396 988 689 224 1014 524 532 1468 1349 1017 1384 251 55